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Research Trials Suggested During the Panel

These trials were proposed in June 2000
during the Internet Discussion
of the South African Presidential AIDS Advisory Panel

The following are some of the trials that I suggested during the Internet discussion of the South African Government AIDS Advisory Panel, to be considered by Dr. Peter Duesberg, Dr. Harvey Bialy, Dr. Helene Gayle, and Prof. William Makgoba when designing experiments to clarify once and for all the real causes of AIDS, its diagnosis, treatment, and prevention.

Please note that I wish to participate actively in these proposed experiments, from the point of designing them with the assistance of epidemiologists and statisticians, through the follow up, and on to their conclusion.

1. To find out the real meaning of the tests for HIV

Take blood from four groups of people and run the tests highly diluted, undiluted and at a wide spectrum of dilutions in between: a) The first group would be a group of healthy people of many different age groups; b) the second group would be a group of people from the AIDS risk groups; c) the third group would be a group of people with clinical conditions unrelated to AIDS; and d) the fourth group would be a group of patients with full manifestations of AIDS.

All groups would be subjected to both ELISA and Western blot tests. Additionally, all plasma samples will be subjected to the viral load test for HIV.

The result of such experiments could determine whether these test measurements bear any relationship to an individual’s level of exposure to stressor or oxidizing agents. If so, the tests could be salvaged as a measure of an individual’s level of intoxication.

The bases and references for these experiments are detailed in my posts: "Tests for HIV are highly inaccurate" and "Everybody is HIV-positive"

2. To find out the real role of co-factors – immunological stressors – in the causation of AIDS

Have three groups of people: a) symptomatic AIDS patients; b) HIV-positive non-symptomatic individuals; and c) very healthy HIV-negative individuals.

The AIDS patients as well as the HIV-positive non-symptomatic groups should have individuals from all the groups at risk for AIDS: drug addicted and non-drug addicted gay males; IV and non-IV drug addicted individuals; prostitutes; hemophiliacs; blacks and Hispanics in the USA; Africans and Asians; children from developed and underdeveloped countries; AIDS-phobic people; and an occupational group. The healthy HIV-negative individuals should be used as controls and should match as closely as possible the individuals in the other two groups.

Retrospective trial ¾ before starting any treatment the three groups should be tested for:

· Exposure to immunological stressors of chemical, physical, biological, mental, and nutritional origin. A questionnaire should be use to determine retrospectively past exposures to chemical, physical, biological, mental, and nutritional immunological stressors.

· Levels of oxidizing agents. Determine for all groups the presence and levels of surrogate markers of oxidation.

· "HIV status." Conduct on all individuals in the three groups ELISA, Western blot and PCR tests.

· Immune system response capabilities. In addition to counting all the T and B cell subsets, it is necessary to evaluate the functioning status of lymphocytes, as well as all other immunocompetent cells, by tests such as lymphoblastotransformation, inhibition of migration, lymphocyte activation, etc. Determine the levels of all components of the complement system. Determine electrophoresis of proteins, immunoelectrophoresis, levels of serum immunoglobulins G, A, M, D, and E. Determine the presence or absence of all types of autoantibodies, circulatory immune complexes, and skin test reactions. Determine Beta 2 microglobulin.

· Physiological status of all other systems. Conduct complete chemical, hematological, urine and stool profiles. Also determine the status of the endocrine glands, liver, and kidneys. Determine levels of micronutrients such as B-complex vitamins, Vitamin C, betacarothene, vitamin E, selenium, zinc, magnesium, etc. Determine Beta 2 microglobulin.

Prospective trial ¾ follow the three groups for several years with periodical clinical and laboratory evaluation of their health status.

Bases and references for these experiments may be seen in my posts: "Co-factors cause AIDS" and "An effective treatment for AIDS"

3. To check whether breastfeeding is or is not a real risk factor for AIDS

The only objective way to confirm the hypothesis of the transmission of HIV/AIDS through breast milk is by searching not only for HIV but also for all other potential risk factors for testing positively on the tests for HIV and for immunodeficiency, in at least four different groups of people:

a) One group of HIV-positive mothers and their infants living in a variety of African conditions; b) one group of HIV-positive mothers and their infants living in a variety of developed conditions; c) one group of HIV-negative mothers and their infants living in a variety of African conditions; d) one group of HIV-negative mothers and their infants living in a variety of developed conditions.

In each group there has to be a significant number of mothers that breastfed, formula fed and mixed fed their babies.

Retrospective trial ¾ each mother will respond a questionnaire with questions looking for past voluntary and involuntary exposure to immunological stressor agents.

Prospective trial ¾ all groups should be followed for several years to determine if seroconversion of children to HIV-positive or the development of AIDS is secondary to exposure to immunological stressors. Both mothers and children should be subjected to periodic clinical and laboratory evaluations of their health status.

Until objectively proven to the contrary, even during the AIDS era breastfeeding is still the best choice!

Bases and references for these experiments can be seen in my posts: "Breastfeeding and AIDS in Africa" and "Tests for HIV are highly inaccurate".

4. To find out whether the treatment of AIDS with anti-retrovirals is or is not more effective than treatment with non-toxic measures

If there remain doubts about the treatment of AIDS the following trial is suggested to determine whether the treatment of AIDS with non-toxic measures is or is not more effective than the current official treatment with anti-retroviral medications.

Two groups of AIDS patients will be necessary: a) a group of patients will be treated with the official anti-retroviral treatment; and b) a second group will be treated using the non-toxic measures suggested in my post on "An Effective Treatment for AIDS." Patients at different stages of AIDS may be necessary.

Both groups should be followed for several years with clinical and laboratory evaluations of their health status.

Bases and references for these experiments can be seen in my posts: "An effective treatment for AIDS" and "Anti-retrovirals cause AIDS".

5. To determine whether the prevention of AIDS with non-toxic measures is or is not more effective than the official prevention

To determine whether the prevention of AIDS with non-toxic measures is or is not more effective than the official prevention techniques it will be necessary to have two groups of HIV-positive non-symptomatic individuals from the different groups of people at risk for AIDS. Both groups need to have individuals from all ages and from developed and underdeveloped countries. The first group of individuals will be treated with the official antiretroviral drugs and the second group will be provided with the non-toxic measures described in my post "An effective treatment for AIDS".

Both groups must be followed for several years with clinical and laboratory evaluations of their health status.

Bases and references for these experiments can be seen in my posts: "An effective prevention for AIDS" and "Anti-retrovirals cause AIDS"

Roberto A. Giraldo
www.RobertoGiraldo.com


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